Zhiyong Zhao Selected Research

Fetal Diseases (Embryopathy)

1/2019	Disturbed intracellular calcium homeostasis in neural tube defects in diabetic embryopathy.
11/2017	Impact of protein O-GlcNAcylation on neural tube malformation in diabetic embryopathy.
9/2016	Reevaluation of Antioxidative Strategies for Birth Defect Prevention in Diabetic Pregnancies.
6/2013	Activin-A in diabetes-induced cardiac malformations in embryos.
8/2012	Reduction in embryonic malformations and alleviation of endoplasmic reticulum stress by nitric oxide synthase inhibition in diabetic embryopathy.
3/2011	Protein kinase Cβ2 inhibition reduces hyperglycemia-induced neural tube defects through suppression of a caspase 8-triggered apoptotic pathway.
4/2010	Cardiac malformations and alteration of TGFbeta signaling system in diabetic embryopathy.
2/2009	Caspase-8: a key role in the pathogenesis of diabetic embryopathy.
3/2008	Blockade of c-Jun N-terminal kinase activation abrogates hyperglycemia-induced yolk sac vasculopathy in vitro.
1/2008	Activation of oxidative stress signaling that is implicated in apoptosis with a mouse model of diabetic embryopathy.

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Zhiyong Zhao Research Topics

Disease

18	Hyperglycemia 02/2022 - 03/2005
16	Fetal Diseases (Embryopathy) 01/2019 - 03/2005
8	Neoplasms (Cancer) 08/2023 - 10/2004
6	Neural Tube Defects (Exencephaly) 01/2019 - 03/2011
5	Congenital Abnormalities (Deformity) 01/2018 - 06/2013
4	Stroke (Strokes) 01/2023 - 01/2018
3	Diabetes Mellitus 11/2017 - 01/2008
2	Sepsis (Septicemia) 01/2024 - 04/2022
2	Infections 12/2023 - 12/2019
2	Shock 01/2023 - 12/2019
2	Cerebral Hemorrhage 01/2022 - 12/2019
2	Lung Neoplasms (Lung Cancer) 09/2021 - 01/2021
2	Inflammation (Inflammations) 09/2021 - 03/2021
2	Adenocarcinoma of Lung 04/2021 - 01/2021
2	Bronchiolitis 01/2020 - 01/2020
1	Metabolic Diseases (Metabolic Disease) 04/2024
1	Hyperuricemia 04/2024
1	Acute Kidney Injury (Acute Renal Failure) 01/2024
1	Adenocarcinoma 01/2024
1	Carcinogenesis 01/2024
1	Stomach Neoplasms (Stomach Cancer) 01/2024
1	Severe Acute Respiratory Syndrome 12/2023
1	Disease Resistance 10/2023
1	Neoplasm Metastasis (Metastasis) 08/2023
1	Situs Inversus 01/2023
1	Breast Neoplasms (Breast Cancer) 12/2022
1	Chronic Subdural Hematoma 03/2022
1	Hematoma 03/2022
1	Critical Illness (Critically Ill) 02/2022
1	Esophageal Squamous Cell Carcinoma 02/2022
1	Autoimmune Diseases (Autoimmune Disease) 01/2022
1	Myocardial Infarction 01/2022
1	Myocarditis (Carditis) 01/2022
1	Pain (Aches) 01/2022
1	Death (Near-Death Experience) 01/2022
1	Nasopharyngeal Carcinoma 01/2022
1	Disease Progression 01/2022
1	Alzheimer Disease (Alzheimer's Disease) 12/2021
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2021

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 12/2022 - 10/2004
4	Biomarkers (Surrogate Marker)IBA 01/2024 - 11/2018
4	Nitric Oxide Synthase (NO Synthase)IBA 01/2018 - 08/2012
3	Messenger RNA (mRNA)IBA 01/2024 - 01/2016
3	CalciumIBA 12/2023 - 10/2005
3	ErbB Receptors (EGF Receptor)IBA 04/2021 - 01/2021
3	AntioxidantsIBA 09/2016 - 12/2005
3	Phosphotransferases (Kinase)IBA 01/2015 - 03/2005
2	LipidsIBA 04/2024 - 02/2006
2	Ascorbic Acid (Vitamin C)FDA LinkGeneric 10/2023 - 10/2005
2	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2023 - 02/2016
2	FlavonoidsIBA 10/2023 - 01/2018
2	Glucose (Dextrose)FDA LinkGeneric 04/2022 - 09/2012
2	Therapeutic UsesIBA 01/2022 - 01/2020
2	AlbuminsIBA 09/2021 - 12/2019
2	IodineIBA 04/2021 - 01/2021
2	InterferonsIBA 01/2020 - 01/2020
2	PhytochemicalsIBA 01/2018 - 02/2016
2	CreatinineIBA 01/2018 - 01/2015
2	Reactive Nitrogen SpeciesIBA 01/2018 - 09/2016
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2016 - 02/2016
2	activin AIBA 10/2014 - 06/2013
2	Streptozocin (Streptozotocin)FDA Link 06/2013 - 01/2008
2	Protein Kinases (Protein Kinase)IBA 10/2012 - 03/2011
2	Caspase 8 (Caspase-8)IBA 03/2011 - 02/2009
2	Caspase 3 (Caspase-3)IBA 03/2011 - 01/2008
2	CaspasesIBA 03/2011 - 02/2009
2	pyrazolanthroneIBA 03/2008 - 06/2007
2	Mitogen-Activated Protein KinasesIBA 02/2006 - 12/2005
1	CholesterolIBA 04/2024
1	Uric Acid (Urate)IBA 04/2024
1	Prothrombin (Factor II)IBA 01/2024
1	Lipocalin-2IBA 01/2024
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 12/2023
1	Glutathione (Reduced Glutathione)IBA 10/2023
1	1-methylcyclopropeneIBA 10/2023
1	Lysine (L-Lysine)FDA Link 10/2023
1	Peptide Hydrolases (Proteases)FDA Link 08/2023
1	NanogelsIBA 01/2023
1	Small Interfering RNA (siRNA)IBA 12/2022
1	Endoplasmic Reticulum Chaperone BiPIBA 04/2022
1	Transcription Factor CHOPIBA 04/2022
1	Blood Glucose (Blood Sugar)IBA 02/2022
1	omega-Chloroacetophenone (Mace)IBA 01/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	tofacitinibIBA 01/2022
1	SteroidsIBA 01/2022
1	tau Proteins (tau Protein)IBA 12/2021
1	IronIBA 12/2021
1	Amyloid beta-PeptidesIBA 12/2021
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 03/2021
1	Tyrosine Kinase InhibitorsIBA 01/2021

Therapy/Procedure

8	Therapeutics 01/2023 - 02/2006
2	Esophagectomy 02/2022 - 01/2021
2	Intravenous Injections 06/2013 - 01/2008
1	Photochemotherapy (Photodynamic Therapy) 01/2023
1	Fluid Therapy (Oral Rehydration Therapy) 01/2023
1	Drug Therapy (Chemotherapy) 01/2023
1	Activities of Daily Living (ADL) 01/2023
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2023
1	Length of Stay 03/2022